Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003152)
Formula
SVG example
Monohydroxylation
Reactant Oxymetazoline metabolite M2 Product Oxymetazoline metabolite M3
Reactant Info Product Info
Metabolic Enzyme Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Metabolic Type Oxidation - Monohydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003156 Oxymetazoline Oxymetazoline metabolite M2 Oxidation - Oxidative Dehydrogenation Oxymetazoline [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003154 Oxymetazoline metabolite M2 Oxymetazoline metabolite M6 Conjugation - Conjugation Oxymetazoline [1]
MR003153 Oxymetazoline metabolite M2 Oxymetazoline metabolite M7 Conjugation - Conjugation Oxymetazoline [1]
References
1 In vitro metabolism of oxymetazoline: evidence for bioactivation to a reactive metabolite. Drug Metab Dispos. 2011 Apr;39(4):693-702.

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