| General Information of This Metabolic Reaction (MR) (ID:
MR003171) |
| Formula |
|
| Reactant |
Fosphenytoin sodium |
Product |
3-hydroxymethylphenytoin |
|
Reactant Info
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Product Info
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Metabolic Enzyme
|
Alkaline phosphatase (ALPL)
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DME Info
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Metabolic Type
|
Hydrolysis
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Hydrolysis
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| Other MR(s) Related to The Product of This MR |
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Other MR(s) That Metabolize The Produtc of This MR
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| References |
| 1 |
Evaluation of in vitro models for screening alkaline phosphatase-mediated bioconversion of phosphate ester prodrugs Drug Metab Dispos. 2009 Jul;37(7):1443-7. doi: 10.1124/dmd.108.026245.
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