Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003216)
Formula
SVG example
Reactant Darolutamide metabolite M31 Product Darolutamide metabolite M26
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003223 Darolutamide Darolutamide metabolite M31 Unclear Darolutamide [1]
MR003210 Ketodarolutamide Darolutamide metabolite M31 Unclear Darolutamide [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003217 Darolutamide metabolite M31 Darolutamide metabolite M30 Reduction - Reduction Darolutamide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003218 Darolutamide metabolite M26 Darolutamide metabolite M25 Oxidation - Hydroxylation Darolutamide [1]
MR003219 Darolutamide metabolite M26 Darolutamide metabolite M29 Oxidation - Hydroxylation Darolutamide [1]
References
1 Metabolism and Mass Balance of the Novel Nonsteroidal Androgen Receptor Inhibitor Darolutamide in Humans Drug Metab Dispos. 2021 Jun;49(6):420-433. doi: 10.1124/dmd.120.000309.

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