Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003218)
Formula
SVG example
Hydroxylation
Reactant Darolutamide metabolite M26 Product Darolutamide metabolite M25
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003216 Darolutamide metabolite M31 Darolutamide metabolite M26 Unclear Darolutamide [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003219 Darolutamide metabolite M26 Darolutamide metabolite M29 Oxidation - Hydroxylation Darolutamide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003221 Darolutamide metabolite M25 Darolutamide metabolite M21 Conjugation - Glucuronidation Darolutamide [1]
MR003220 Darolutamide metabolite M25 Darolutamide metabolite M24 Unclear Darolutamide [1]
References
1 Metabolism and Mass Balance of the Novel Nonsteroidal Androgen Receptor Inhibitor Darolutamide in Humans Drug Metab Dispos. 2021 Jun;49(6):420-433. doi: 10.1124/dmd.120.000309.

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