Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003280)
Formula
SVG example
Reactant 4-hydroxytriazolame Product HM-CTB
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003285 Triazolam 4-hydroxytriazolame Oxidation - 4-Hydroxylation Triazolam [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003281 4-hydroxytriazolame M-CTB Unclear Triazolam [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003282 HM-CTB HH-CTB Unclear Triazolam [1], [2]
References
1 Triazolam disposition Clin Pharmacol Ther. 1981 Jan;29(1):81-93. doi: 10.1038/clpt.1981.14.
2 Triazolam substrate inhibition: evidence of competition for heme-bound reactive oxygen within the CYP3A4 active site. Drug Metab Dispos. 2001 Jan;29(1):70-5.

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