Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003372)
Formula
SVG example
Hydrolysis
Reactant Aceclofenac Product Diclofenac
Reactant Info Product Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003371 Aceclofenac 4'-hydroxyaceclofenac Oxidation - 4'-Hydroxylation Aceclofenac [1]
MR003373 Aceclofenac 5-hydroxyaceclofenac Oxidation - 5-Hydroxylation Aceclofenac [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003370 Diclofenac 4'-hydroxydiclofenac Unclear Aceclofenac [2]
References
1 DrugBank(Pharmacology-Metabolism)Aceclofenac
2 Modeling of aceclofenac metabolism to major metabolites in healthy volunteers Drug Metab Pharmacokinet. 2016 Dec;31(6):458-463. doi: 10.1016/j.dmpk.2016.10.001.

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