Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003402)
Formula Reactant Febuxostat Product Febuxostat acyl-glucuronide
Reactant Info Product Info
Metabolic Type Conjugation - Conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003399 Febuxostat Febuxostat metabolite 67M-1 Oxidation - Oxidation Febuxostat [1]
MR003400 Febuxostat Febuxostat metabolite 67M-2 Oxidation - Oxidation Febuxostat [1]
MR003401 Febuxostat Febuxostat metabolite 67M-3 Oxidation - Oxidation Febuxostat [1]
References
1 In vitro drug-drug interaction studies with febuxostat, a novel non-purine selective inhibitor of xanthine oxidase: plasma protein binding, identification of metabolic enzymes and cytochrome P450 inhibition. Xenobiotica. 2008 May;38(5):496-510.

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