Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003641)
Formula
SVG example
Hydrolyzationn
Reactant THC Product 11-OH-THC
Reactant Info Product Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003640 GW-1000 THC Unclear GW-1000 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003648 THC THC-glucuronide Unclear GW-1000 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006696 Dronabinol 11-OH-delata-Tetrahydrocannabinol Oxidation - Aliphatic hydroxylation Dronabinol [2], [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003642 11-OH-THC THC-COOH Oxidation - Oxidationn GW-1000 [1]
References
1 Techniques and technologies for the bioanalysis of Sativex?, metabolites and related compounds
2 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
3 Cytochromes P450: a structure-based summary of biotransformations using representative substrates Drug Metab Rev. 2008;40(1):1-100. doi: 10.1080/03602530802309742.

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