Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003771)
Formula Reactant MK-0859 Metabolite M1 Product MK-0859 Metabolite M13
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003763 MK-0859 MK-0859 Metabolite M1 Oxidation - O-demethylation MK-0859 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003772 MK-0859 Metabolite M1 MK-0859 Metabolite M10 Conjugation - Glucuronidation MK-0859 [2]
MR003764 MK-0859 Metabolite M1 MK-0859 Metabolite M2 Oxidation - Hydrolyzationn MK-0859 [1]
MR003768 MK-0859 Metabolite M1 MK-0859 Metabolite M3 Oxidation - Hydrolyzationn MK-0859 [1]
MR003773 MK-0859 Metabolite M1 MK-0859 Metabolite M4 Unclear MK-0859 [2]
References
1 Metabolism and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in humans. Drug Metab Dispos. 2010 Mar;38(3):474-83.
2 Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys

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