Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003775)
Formula Reactant MK-0859 Product MK-0859 Metabolite M6
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003763 MK-0859 MK-0859 Metabolite M1 Oxidation - O-demethylation MK-0859 [1]
MR003774 MK-0859 MK-0859 Metabolite M11 Oxidation - Oxidationn MK-0859 [2]
References
1 Metabolism and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in humans. Drug Metab Dispos. 2010 Mar;38(3):474-83.
2 Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys

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