Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003841)
Formula
CYP2C9 ...
SVG example
Dehydrogenation
Reactant BE-14348A Product Apigenin
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Oxidation - Dehydrogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003833 BE-14348A 3-(4-Hydroxyphenyl) propionic acid Unclear BE-14348A [1]
MR003842 BE-14348A 5,7-Dihydroxychromone Unclear BE-14348A [2]
MR003839 BE-14348A Eriodictyol Oxidation - Hydrolyzationn BE-14348A [2]
MR003843 BE-14348A Naringenin-O-glucuronides Conjugation - Glucuronidation BE-14348A [2]
MR003844 BE-14348A Phloroglucinol Unclear BE-14348A [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004332 Naringenin Apigenin Reduction - Hydrogenation Naringin [3]
References
1 High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism
2 Pharmacokinetics and Metabolism of Naringin and Active Metabolite Naringenin in Rats, Dogs, Humans, and the Differences Between Species
3 Microbial Metabolism of Naringin and the Impact on Antioxidant Capacity

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