Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003853)
Formula
SVG example
Reactant Bile acid Product LCA
Reactant Info Product Info
Metabolic Enzyme 7alpha-dehydroxylase (DEH7A) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003845 Bile acid Alpha-MCA Unclear Bile acid [1]
MR003854 Bile acid Hyocholic acid Unclear Bile acid [1]
MR003848 Bile acid UDCA Unclear Bile acid [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002540 Chenodeoxycholic acid Lithocholic acid Unclear Chenodeoxycholic acid [2]
MR002483 Ursodeoxycholic acid Lithocholic acid Unclear Ursodeoxycholic acid [3]
MR003850 UDCA LCA Unclear Bile acid [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003851 LCA Hyodexycholic acid Unclear Bile acid [1]
MR003852 LCA Murideoxycholic acid Unclear Bile acid [1]
References
1 Bile Acid Metabolism in Liver Pathobiology
2 Identification of human hepatic cytochrome p450 enzymes involved in the biotransformation of cholic and chenodeoxycholic acid. Drug Metab Dispos. 2008 Oct;36(10):1983-91.
3 Pharmacology of ursodeoxycholic acid, an enterohepatic drug Scand J Gastroenterol Suppl. 1994;204:1-15. doi: 10.3109/00365529409103618.

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