Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003917)
Formula Reactant H3B-6527 Metabolite M936 Product H3B-6527 Metabolite M807
Reactant Info Product Info
Metabolic Enzyme Gamma-glutamyltranspeptidase 5 (GGT5) DME Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003916 H3B-6527 H3B-6527 Metabolite M936 Unclear H3B-6527 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003918 H3B-6527 Metabolite M807 H3B-6527 Metabolite M750 Unclear H3B-6527 [1]
References
1 Correlation of the in vitro biotransformation of H3B-6527 in dog and human hepatocytes with the in vivo metabolic profile of 14C-H3B-6527 in a dog mass balance study. Xenobiotica. 2020 Apr;50(4):458-467.

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