Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003916)
Formula Reactant H3B-6527 Product H3B-6527 Metabolite M936
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003920 H3B-6527 H3B-6527 Metabolite M645 Unclear H3B-6527 [1]
MR003919 H3B-6527 H3B-68730 Oxidation - N-deethylation H3B-6527 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003917 H3B-6527 Metabolite M936 H3B-6527 Metabolite M807 Hydrolysis - Hydrolysis H3B-6527 [1]
References
1 Correlation of the in vitro biotransformation of H3B-6527 in dog and human hepatocytes with the in vivo metabolic profile of 14C-H3B-6527 in a dog mass balance study. Xenobiotica. 2020 Apr;50(4):458-467.

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