Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004015)
Formula Reactant Ketones Product CHOL
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004014 Unifac-6550 Ketones Unclear Unifac-6550 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004017 Ketones MONO Unclear Unifac-6550 [1]
MR004016 Ketones SAT Unclear Unifac-6550 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006263 Desmosterol Cholesterol Unclear Desmosterol [2]
MR002979 Mevalonate Cholesterol Unclear - Unclear Acetyl-CoA [3], [4], [5]
References
1 Carbon recycling into de novo lipogenesis is a major pathway in neonatal metabolism of linoleate and alpha-linolenate
2 Identification and characterization of prescription drugs that change levels of 7-dehydrocholesterol and desmosterol
3 Compartmentalised acyl-CoA metabolism and roles in chromatin regulation Mol Metab. 2020 Aug;38:100941. doi: 10.1016/j.molmet.2020.01.005.
4 Early hyperlipidemia triggers metabolomic reprogramming with increased SAH, increased acetyl-CoA-cholesterol synthesis, and decreased glycolysis. Redox Biol. 2023 Jun 16;64:102771. doi: 10.1016/j.redox.2023.102771.
5 (2)H,(13)C-Cholesterol for Dynamics and Structural Studies of Biological Membranes. ACS Omega. 2022 May 10;7(20):17151-17160. doi: 10.1021/acsomega.2c00796.

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