Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006263)
Formula
SVG example
Reactant Desmosterol Product Cholesterol
Reactant Info Product Info
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004015 Ketones CHOL Unclear Unifac-6550 [1]
MR002979 Mevalonate Cholesterol Unclear - Unclear Acetyl-CoA [2], [3], [4]
References
1 Carbon recycling into de novo lipogenesis is a major pathway in neonatal metabolism of linoleate and alpha-linolenate
2 Compartmentalised acyl-CoA metabolism and roles in chromatin regulation Mol Metab. 2020 Aug;38:100941. doi: 10.1016/j.molmet.2020.01.005.
3 Early hyperlipidemia triggers metabolomic reprogramming with increased SAH, increased acetyl-CoA-cholesterol synthesis, and decreased glycolysis. Redox Biol. 2023 Jun 16;64:102771. doi: 10.1016/j.redox.2023.102771.
4 (2)H,(13)C-Cholesterol for Dynamics and Structural Studies of Biological Membranes. ACS Omega. 2022 May 10;7(20):17151-17160. doi: 10.1021/acsomega.2c00796.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.