Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004242)
Formula
SVG example
Reactant Estrone sulfate Product Estriol
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004243 Estrone sulfate Estradiol-17 beta Unclear Estrone sulfate [1]
MR004241 Estrone sulfate Estrone Unclear Estrone sulfate [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000966 Estropipate Estriol Unclear Estropipate [3]
MR004102 Estrone Estriol Oxidation - Hydrolyzationn Conjugated estrogens [4]
MR013312 16-alpha hydroxyestrone Estriol Unclear E-3A [5]
MR003144 17-beta-estradiol Estriol Unclear Dehydroepiandrosterone [6]
MR002639 16alpha hydroxyestrone Estriol Unclear Estradiol acetate [5]
MR002662 16alpha hydroxyestrone Estriol Unclear Estradiol cypionate [5]
MR002685 16alpha hydroxyestrone Estriol Unclear Estradiol valerate [5]
⏷ Show the Full List of MR
References
1 Metabolism of estrone sulfate by normal breast tissue: influence of menopausal status and oral contraceptives
2 Estrone Sulfate Transport and Steroid Sulfatase Activity in Colorectal Cancer: Implications for Hormone Replacement Therapy
3 DrugBank(Pharmacology-Metabolism)Estropipate
4 DrugBank(Pharmacology-Metabolism):Conjugated estrogens
5 Cytochrome P450 1A2 (CYP1A2) activity and risk factors for breast cancer: a cross-sectional study. Breast Cancer Res. 2004;6(4):R352-65.
6 Resveratrol Inhibits Key Steps of Steroid Metabolism in a Human Estrogen-Receptor Positive Breast Cancer Model: Impact on Cellular Proliferation Front Pharmacol. 2018 Jul 10;9:742. doi: 10.3389/fphar.2018.00742.

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