Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004363)
Formula Reactant Nitrobenzanthrone Product 3-OH-ABA
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A1 (CYP1A1) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Quinone reductase 1 (NQO1) DME Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004372 Nitrobenzanthrone 2-(2'-deoxyguanosin-N2-yl)-3-aminobenzanthrone Unclear Nitrobenzanthrone [1]
MR004373 Nitrobenzanthrone N-(2'-deoxyguanosin-8-yl)-3-aminobenzanthrone Unclear Nitrobenzanthrone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004370 3-OH-ABA 2-(2'-deoxyguanosin-N2-yl)-3-aminobenzanthrone Unclear Nitrobenzanthrone [1]
MR004366 3-OH-ABA 3-Aco-ABA Unclear Nitrobenzanthrone [1]
MR004364 3-OH-ABA 3-aminobenzanthrone Reduction - Reduction Nitrobenzanthrone [1]
MR004368 3-OH-ABA 3-OS-ABA Unclear Nitrobenzanthrone [1]
MR004371 3-OH-ABA N-(2'-deoxyguanosin-8-yl)-3-aminobenzanthrone Unclear Nitrobenzanthrone [1]
References
1 Activation of 3-nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells

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