Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004642)
Formula
SVG example
Dehydrogenation
Reactant 3-Hydroxyibuprofen Product Carboxy-ibuprofen
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Metabolic Type Oxidation - Dehydrogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010035 Dexibuprofen 3-Hydroxyibuprofen Unclear - Unclear Dexibuprofen [1]
MR004641 Ibuprofen 3-Hydroxyibuprofen Oxidation - 3-hydroxylation Ibuprofen [2]
References
1 DrugBank(Pharmacology-Metabolism):Dexibuprofen
2 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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