Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004797)
Formula
SVG example
Reactant Montelukast 1, 2-Diol Product Montelukast dicarboxylic acid
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C8 (CYP2C8) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004796 Montelukast sodium Montelukast 1, 2-Diol Oxidation - Aliphatic hydroxylation Montelukast sodium [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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