Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004841)
Formula Reactant 6-methoxy-2-naphthylacetic acid Product 6-hydroxy-naphthylacetic acid
Reactant Info Product Info
Metabolic Type Oxidation - O-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004840 3-OH-nabumetone 6-methoxy-2-naphthylacetic acid Oxidation - Dealkylation Nabumetone [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004844 6-methoxy-2-naphthylacetic acid 6-methoxy-naphthylacetic acid glucuronide Conjugation - O-glucuronidation Nabumetone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004843 6-hydroxy-naphthylacetic acid 6-hydroxy-naphthylacetic acid glucuronide Conjugation - O-glucuronidation Nabumetone [1]
MR004842 6-hydroxy-naphthylacetic acid 6-hydroxy-naphthylacetic acid sulfate Conjugation - Sulfonation Nabumetone [1]
References
1 Clinical pharmacokinetics of nabumetone. The dawn of selective cyclo-oxygenase-2 inhibition?

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