Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004850)
Formula
SVG example
Hydrolyzationn
Reactant Nalidixic acid Product 7-hydroxymethyl nalidixic acid
Reactant Info Product Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004855 Nalidixic acid Nalidixic acid glucuronide Unclear Nalidixic acid [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004851 7-hydroxymethyl nalidixic acid 7-carboxy nalidixic acid Oxidation - Oxidationn Nalidixic acid [2]
MR004853 7-hydroxymethyl nalidixic acid 7-hydroxymethyl nalidixic acid acylglucuronide Unclear Nalidixic acid [1]
References
1 Probenecid inhibits the renal clearance and renal glucuronidation of nalidixic acid. A pilot experiment
2 Pharmacokinetics of nalidixic acid in man: hydroxylation and glucuronidation

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