Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004851)
Formula Reactant 7-hydroxymethyl nalidixic acid Product 7-carboxy nalidixic acid
Reactant Info Product Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004850 Nalidixic acid 7-hydroxymethyl nalidixic acid Oxidation - Hydrolyzationn Nalidixic acid [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004853 7-hydroxymethyl nalidixic acid 7-hydroxymethyl nalidixic acid acylglucuronide Unclear Nalidixic acid [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004852 7-carboxy nalidixic acid 7-carboxy nalidixic acid glucuronide Unclear Nalidixic acid [3]
References
1 Pharmacokinetics of nalidixic acid in man: hydroxylation and glucuronidation
2 Probenecid inhibits the renal clearance and renal glucuronidation of nalidixic acid. A pilot experiment
3 #N/A

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