Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005074)
Formula
SVG example
Reactant Haloperidol reduced pyridinium ion derivative Product Haloperidol pyridinium ion derivative
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005073 Reduced haloperidol Haloperidol reduced pyridinium ion derivative Unclear Haloperidol decanoate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005080 Haloperidol decanoate 4-(4-Chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-pyridinium (HPP+) Unclear Haloperidol decanoate [2]
MR005076 Haloperidol 1,2,3,6-tetrahydropyridine Haloperidol pyridinium ion derivative Unclear Haloperidol decanoate [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 DrugBank(Pharmacology-Metabolism):Haloperidol decanoate

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