Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005128)
Formula
HSD11B1 ...
SVG example
Oxidationn
Reactant Hydrocortisone Product Cortisone
Reactant Info Product Info
Metabolic Enzyme Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) DME Info
Corticosteroid 11-beta-dehydrogenase 2 (HSD11B2) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005124 Hydrocortisone Tetrahydrocortisol Glucuronide 1 Conjugation - O-glucuronidation Hydrocortisone [1]
MR005125 Hydrocortisone Tetrahydrocortisol Glucuronide 2 Conjugation - O-glucuronidation Hydrocortisone [1]
MR005126 Hydrocortisone Tetrahydrocortisone Glucuronide 1 Conjugation - O-glucuronidation Hydrocortisone [1]
MR005127 Hydrocortisone Tetrahydrocortisone Glucuronide 2 Conjugation - O-glucuronidation Hydrocortisone [1]
References
1 Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor

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