Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005240)
Formula	N-demethylation
	Reactant	Roxithromycin metabolite M2	Product	Roxithromycin metabolite M5
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - N-demethylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005239	Roxithromycin	Roxithromycin metabolite M2	Oxidation - O-dealkylation	Roxithromycin	[1], [2]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005241	Roxithromycin metabolite M5	Roxithromycin metabolite M7	Oxidation - N-demethylation	Roxithromycin	[1], [2]

References
1	Metabolism of roxithromycin in phenobarbital-treated rat liver microsomes
2	Identification of the metabolites of roxithromycin in humans

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