Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005239)
Formula
SVG example
O-dealkylation
Reactant Roxithromycin Product Roxithromycin metabolite M2
Reactant Info Product Info
Metabolic Type Oxidation - O-dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005244 Roxithromycin Descladinose roxithromycin Unclear Roxithromycin [1]
MR005245 Roxithromycin N-di-demethyl roxithromycin Oxidation - N-demethylation Roxithromycin [2], [1]
MR005246 Roxithromycin N-mono roxithromycin Oxidation - N-demethylation Roxithromycin [2], [1]
MR005242 Roxithromycin Roxithromycin metabolite M4 Oxidation - O-demethylation Roxithromycin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005240 Roxithromycin metabolite M2 Roxithromycin metabolite M5 Oxidation - N-demethylation Roxithromycin [2], [1]
References
1 Identification of the metabolites of roxithromycin in humans
2 Metabolism of roxithromycin in phenobarbital-treated rat liver microsomes

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