General Information of This Metabolic Reaction (MR) (ID: MR005466)
Formula
XDH ...
SVG example
Reactant Capmatinib Product Capmatinib M19
Reactant Info Product Info
Metabolic Enzyme Xanthine dehydrogenase/oxidase (XDH) DME Info
Aldehyde oxidase (AOX1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005461 Capmatinib Capmatinib M13 Unclear Capmatinib [1]
MR005464 Capmatinib Capmatinib M16 Unclear Capmatinib [1]
MR005450 Capmatinib Capmatinib M18 Unclear Capmatinib [1]
MR005467 Capmatinib Capmatinib M21 Unclear Capmatinib [1]
MR005455 Capmatinib Capmatinib M26 Reduction - Hydrogenation Capmatinib [1]
MR005468 Capmatinib Capmatinib M41 Unclear Capmatinib [1]
MR005469 Capmatinib Capmatinib M48 Unclear Capmatinib [1]
MR005465 Capmatinib Capmatinib M8 Unclear Capmatinib [1]
References
1 Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite

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