Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005492)
Formula Reactant Fostemsavir M27 Product Fostemsavir M22
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005491 Temsavir Fostemsavir M27 Oxidation - Mono-oxidation Fostemsavir [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005496 Fostemsavir M27 Fostemsavir M10 Unclear Fostemsavir [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005493 Fostemsavir M22 Fostemsavir M31 Unclear Fostemsavir [1]
References
1 Pharmacokinetics, metabolism and excretion of radiolabeled fostemsavir administered with or without ritonavir in healthy male subjects

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