Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005502)
Formula Reactant Fostemsavir M4 Product Fostemsavir M16
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005501 Temsavir Fostemsavir M4 Hydrolysis - Amide hydrolysis Fostemsavir [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005503 Fostemsavir M4 Fostemsavir M1 Unclear Fostemsavir [1]
MR005504 Fostemsavir M4 Fostemsavir M2 Unclear Fostemsavir [1]
MR005505 Fostemsavir M4 Fostemsavir M3 Unclear Fostemsavir [1]
References
1 Pharmacokinetics, metabolism and excretion of radiolabeled fostemsavir administered with or without ritonavir in healthy male subjects

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