Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005605)
Formula Reactant PKB-CoA Product PA-CoA
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005604 PHB-CoA PKB-CoA Unclear Sodium phenylbutyrate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005606 Sodium phenylbutyrate Phenylacetyl-CoA Oxidation - Oxidationn Sodium phenylbutyrate [2]
MR005601 Beta-Ketophenylbutyryl-CoA Phenylacetyl-CoA Unclear Sodium phenylbutyrate [2]
MR013770 Beta-Ketophenylbutyryl-CoA Phenylacetyl-CoA Unclear - Unclear phenylbutyrate [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005607 Phenylacetyl-CoA Phenylacetylglutamine Unclear Sodium phenylbutyrate [2]
References
1 Identification of enzymes involved in oxidation of phenylbutyrate
2 Evidence for involvement of medium chain acyl-CoA dehydrogenase in the metabolism of phenylbutyrate
3 Phase 2 comparison of a novel ammonia scavenging agent with sodium phenylbutyrate in patients with urea cycle disorders: safety, pharmacokinetics and ammonia control

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