Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005606)
Formula
SVG example
Oxidationn
Reactant Sodium phenylbutyrate Product Phenylacetyl-CoA
Reactant Info Product Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005608 Sodium phenylbutyrate Phenylacetic acid Oxidation - Oxidationn Sodium phenylbutyrate [1]
MR005596 Sodium phenylbutyrate Phenylbutyryl-CoA Unclear Sodium phenylbutyrate [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005601 Beta-Ketophenylbutyryl-CoA Phenylacetyl-CoA Unclear Sodium phenylbutyrate [2]
MR013770 Beta-Ketophenylbutyryl-CoA Phenylacetyl-CoA Unclear - Unclear phenylbutyrate [3]
MR005605 PKB-CoA PA-CoA Unclear Sodium phenylbutyrate [4]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005607 Phenylacetyl-CoA Phenylacetylglutamine Unclear Sodium phenylbutyrate [2]
References
1 DrugBank(Pharmacology-Metabolism):Sodium phenylbutyrate
2 Evidence for involvement of medium chain acyl-CoA dehydrogenase in the metabolism of phenylbutyrate
3 Phase 2 comparison of a novel ammonia scavenging agent with sodium phenylbutyrate in patients with urea cycle disorders: safety, pharmacokinetics and ammonia control
4 Identification of enzymes involved in oxidation of phenylbutyrate

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