General Information of This Metabolic Reaction (MR) (ID: MR005617)
Formula Reactant Selumetinib M2 (amide glucuronide selumetinib metabolite) Product Selumetinib M1 selumetinib metabolite
Reactant Info Product Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005616 Selumetinib M14 (AZ12791138) Selumetinib M2 (amide glucuronide selumetinib metabolite) Conjugation - Glucuronidation Selumetinib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005618 Selumetinib M2 (amide glucuronide selumetinib metabolite) Selumetinib M6 selumetinib metabolite Oxidation - Oxidationn Selumetinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005613 Selumetinib M10 selumetinib metabolite Selumetinib M1 selumetinib metabolite Oxidation - Oxidationn Selumetinib [1]
References
1 Metabolism, Excretion, and Pharmacokinetics of Selumetinib, an MEK1/2 inhibitor, in Healthy Adult Male Subjects

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