Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005613)
Formula	Reactant	Selumetinib M10 selumetinib metabolite	Product	Selumetinib M1 selumetinib metabolite
Formula	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - Oxidationn

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005612	Selumetinib M12 (Primary amide, N-demethylated selumetinib metabolite)	Selumetinib M10 selumetinib metabolite	Oxidation - Oxidationn	Selumetinib	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR005617	Selumetinib M2 (amide glucuronide selumetinib metabolite)	Selumetinib M1 selumetinib metabolite	Oxidation - Oxidationn	Selumetinib	[1]

References
1	Metabolism, Excretion, and Pharmacokinetics of Selumetinib, an MEK1/2 inhibitor, in Healthy Adult Male Subjects

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