Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005667)
Formula
UGT2B7 ...
SVG example
Reactant Vorinostat Product Vorinostat-O-Glucuronide metabolite
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
UDP-glucuronosyltransferase 1A10 (UGT1A10) DME Info
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info
UDP-glucuronosyltransferase 1A8 (UGT1A8) DME Info
UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info
UDP-glucuronosyltransferase 2B17 (UGT2B17) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005666 Vorinostat 4-anilino-4-oxobutanoic acid Unclear Vorinostat [1], [2]
References
1 Stability studies of vorinostat and its two metabolites in human plasma, serum and urine
2 Uridine 5'-diphospho-glucuronosyltransferase genetic polymorphisms and response to cancer chemotherapy. Future Oncol. 2010 Apr;6(4):563-85.

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