Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005681)
Formula
SVG example
Deamination
Reactant N-Desmethylzolmitriptan Product Indole ethyl alcohol zolmitriptan derivative
Reactant Info Product Info
Metabolic Enzyme Monoamine oxidase type A (MAO-A) DME Info
Metabolic Type Oxidation - Deamination
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005680 Zolmitriptan N-Desmethylzolmitriptan Oxidation - N-dealkylation Zolmitriptan [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005682 Indole ethyl alcohol zolmitriptan derivative Indole acetic acid zolmitriptan derivative Oxidation - Oxidationn Zolmitriptan [1], [2]
References
1 Indolealkylamines: biotransformations and potential drug-drug interactions
2 Determination of the human cytochrome P450 isoforms involved in the metabolism of zolmitriptan. Xenobiotica. 1999 Aug;29(8):847-57.

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