General Information of This Metabolic Reaction (MR) (ID: MR005736)
Formula
RDH5 ...
SVG example
Reactant Retinal Product Retinol
Reactant Info Product Info
Metabolic Enzyme Retinol dehydrogenase 5 (RDH5) DME Info
DME Info
Short-chain dehydrogenase/reductase retSDR8 (DHRS9) DME Info
Retinol-binding protein 1 (RBP1) DME Info
Retinol-binding protein 2 (RBP2) DME Info
Retinol-binding protein 4 (RBP4) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005730 Beta carotene Retinal Unclear Beta carotene [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005731 Retinal Retinoic acid Unclear Beta carotene [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000143 All-trans-retinal Retinol Unclear All-trans-retinal [2], [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000142 Retinol Retinyl esters Unclear All-trans-retinal [2], [3]
MR005737 Retinol Dihydroretinol Unclear Beta carotene [1]
References
1 #NAME?
2 Metabolism of retinaldehyde isomers in pregnant rats: 13-cis- and all-trans-retinaldehyde, but not 9-cis-retinaldehyde, yield very similar patterns of retinoid metabolites Drug Metab Dispos. 1999 Mar;27(3):317-21.
3 PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle. Cell Rep. 2023 Feb 8;42(2):112091. doi: 10.1016/j.celrep.2023.112091.

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