Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005737)
Formula
SVG example
Reactant Retinol Product Dihydroretinol
Reactant Info Product Info
Metabolic Enzyme Retinoid isomerohydrolase (RPE65) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000143 All-trans-retinal Retinol Unclear All-trans-retinal [1], [2]
MR005736 Retinal Retinol Unclear Beta carotene [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000142 Retinol Retinyl esters Unclear All-trans-retinal [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005738 Dihydroretinol Dihydroretinoic acid Unclear Beta carotene [3]
References
1 Metabolism of retinaldehyde isomers in pregnant rats: 13-cis- and all-trans-retinaldehyde, but not 9-cis-retinaldehyde, yield very similar patterns of retinoid metabolites Drug Metab Dispos. 1999 Mar;27(3):317-21.
2 PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle. Cell Rep. 2023 Feb 8;42(2):112091. doi: 10.1016/j.celrep.2023.112091.
3 #NAME?

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