Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005790)
Formula
SVG example
Reactant Deamido-NAD Product NAD+
Reactant Info Product Info
Metabolic Enzyme Glutamine-dependent NAD(+) synthetase (NADSYN1) DME Info
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004388 NMN zwitterion NAD+ Unclear NMN zwitterion [1]
MR004348 Nicotinamide (NAM) Nicotinamide adenine dinucleotide Unclear Nicotinate-MN [2]
MR012862 NaAD+ NAD+ Unclear D-ribosylnicotinate [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004389 NAD+ Nicotinamide (NAM) Unclear NMN zwitterion [1]
MR005791 NAD+ Nicotinamide (NAM) Unclear Deamido-NAD [4]
MR012863 NAD+ Nicotinamide (NAM) Unclear D-ribosylnicotinate [3]
References
1 #NAME?
2 Effects of formulation design on niacin therapeutics: mechanism of action, metabolism, and drug delivery
3 Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism
4 Molecular identification of human glutamine- and ammonia-dependent NAD synthetases. Carbon-nitrogen hydrolase domain confers glutamine dependency. J Biol Chem. 2003 Mar 28;278(13):10914-21.

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