Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005829)
Formula
SVG example
Hydrolyzationn
Reactant Mequitazine Product Hydroxy-Mequitazine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005828 Mequitazine Mequitazine S-oxide Oxidation - S-oxidation Mequitazine [1]
References
1 Oxidation of histamine H1 antagonist mequitazine is catalyzed by cytochrome P450 2D6 in human liver microsomes. J Pharmacol Exp Ther. 1998 Feb;284(2):437-42.

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