Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005872)
Formula Reactant Liquiritin metabolite M7 Product Liquiritin metabolite M9
Reactant Info Product Info
Metabolic Type Other reaction - Ring cleavage reaction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005871 Liquiritin Liquiritin metabolite M7 Multi-steps Reaction - Ring cleavage reaction; hydrolysis Liquiritin [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005878 Liquiritin metabolite M7 Liquiritin metabolite M12 Conjugation - Glucose Conjugation Liquiritin [1]
MR005877 Liquiritin metabolite M7 Liquiritin metabolite M8 Reduction - Hydrogenation Liquiritin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008830 Cetraxate PHPA Hydrolysis - Hydrolysis Cetraxate [2]
MR006957 Naringenin 3-(4-Hydroxyphenyl)propionic acid Unclear CCG-208408 [3]
MR013569 5-(3',4'-dihydroxyphenyl)-propionic acid 3-(4'-hydroxyphenyl)-propionic acid Unclear Epigallocatechin gallate [4]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006958 3-(4-Hydroxyphenyl)propionic acid 3-(4'-Hydroxyphenyl)acetic acid Unclear CCG-208408 [3]
MR006961 3-(4-Hydroxyphenyl)propionic acid 3-(Phenyl)propionic acid Unclear CCG-208408 [3]
MR005876 Liquiritin metabolite M9 Liquiritin metabolite M10 Oxidation - Dehydrogenation Liquiritin [1]
MR005873 Liquiritin metabolite M9 Liquiritin metabolite M11 Other reaction - Degradation Liquiritin [1]
References
1 A comprehensive profiling and identification of liquiritin metabolites in rats using ultra-high-performance liquid chromatography coupled with linear ion trap-orbitrap mass spectrometer
2 [Pharmacokinetic and pharmacological studies on cetraxate, an anti-ulcer agent]
3 Catabolism of citrus flavanones by the probiotics Bifidobacterium longum and Lactobacillus rhamnosus. Eur J Nutr. 2018 Feb;57(1):231-242.
4 Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate

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