Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005876)
Formula Reactant Liquiritin metabolite M9 Product Liquiritin metabolite M10
Reactant Info Product Info
Metabolic Type Oxidation - Dehydrogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008830 Cetraxate PHPA Hydrolysis - Hydrolysis Cetraxate [1]
MR005872 Liquiritin metabolite M7 Liquiritin metabolite M9 Other reaction - Ring cleavage reaction Liquiritin [2]
MR006957 Naringenin 3-(4-Hydroxyphenyl)propionic acid Unclear CCG-208408 [3]
MR013569 5-(3',4'-dihydroxyphenyl)-propionic acid 3-(4'-hydroxyphenyl)-propionic acid Unclear Epigallocatechin gallate [4]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006958 3-(4-Hydroxyphenyl)propionic acid 3-(4'-Hydroxyphenyl)acetic acid Unclear CCG-208408 [3]
MR006961 3-(4-Hydroxyphenyl)propionic acid 3-(Phenyl)propionic acid Unclear CCG-208408 [3]
MR005873 Liquiritin metabolite M9 Liquiritin metabolite M11 Other reaction - Degradation Liquiritin [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004310 Naringenin p-Coumaric acid Other reaction - Ring cleavage reaction Naringin [5]
MR004397 3-(4-Hydroxyphenyl)propanoic acid (2E)-3-(4-Hydroxyphenyl)prop-2-enoic acid Unclear N-nonylphenol [6]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004311 p-Coumaric acid 3-(4'-hydroxyphenyl)propionic acid Reduction - Hydrogenation Naringin [5]
MR004314 p-Coumaric acid Caffeic acid Oxidation - Hydrolyzationn Naringin [5]
MR004315 p-Coumaric acid Cinnamic acid Reduction - Dehydroxylation Naringin [5]
MR004405 (2E)-3-(4-Hydroxyphenyl)prop-2-enoic acid (2E)-3-(3,4-Dihydroxyphenyl)prop-2-enoic acid Oxidation - Hydrolyzationn N-nonylphenol [6]
MR004398 (2E)-3-(4-Hydroxyphenyl)prop-2-enoic acid 2-(4-Hydroxyphenyl)acetic acid Unclear N-nonylphenol [6]
References
1 [Pharmacokinetic and pharmacological studies on cetraxate, an anti-ulcer agent]
2 A comprehensive profiling and identification of liquiritin metabolites in rats using ultra-high-performance liquid chromatography coupled with linear ion trap-orbitrap mass spectrometer
3 Catabolism of citrus flavanones by the probiotics Bifidobacterium longum and Lactobacillus rhamnosus. Eur J Nutr. 2018 Feb;57(1):231-242.
4 Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate
5 Microbial Metabolism of Naringin and the Impact on Antioxidant Capacity
6 4-n-nonylphenol degradation by the genus Metarhizium with cytochrome P450 involvement

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