Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006051)
Formula
CYP2E1 ...
SVG example
Aromatic hydroxylation
Reactant ENT-1814 Product Hydroquinone
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2E1 (CYP2E1) DME Info
Cytochrome P450 2F1 (CYP2F1) DME Info
Metabolic Type Oxidation - Aromatic hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006054 ENT-1814 Phenyl glucuronide Conjugation - Conjugation ENT-1814 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007413 CoQ-10 Hydroquinone Reduction - Reduction CoQ-10 [2]
MR008146 Quinone Hydroquinone Unclear - Unclear Phytonadione [3]
References
1 Cytochrome P450 isozymes involved in the metabolism of phenol, a benzene metabolite. Toxicol Lett. 2001 Dec 15;125(1-3):117-23.
2 Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics
3 Recent trends in the metabolism and cell biology of vitamin K with special reference to vitamin K cycling and MK-4 biosynthesis

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