Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008146)
Formula
SVG example
Unclear
Reactant Quinone Product Hydroquinone
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007627 Quinone Tetrahydroxydipheno-o-quinone Unclear Pyrogallol [1]
MR007419 Quinone CE-122738 Unclear CP-122721 [2], [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007413 CoQ-10 Hydroquinone Reduction - Reduction CoQ-10 [4]
MR006051 ENT-1814 Hydroquinone Oxidation - Aromatic hydroxylation ENT-1814 [5]
References
1 Metabolism of pyrogallol to purpurogallin by human erythrocytic hemoglobin
2 In vitro metabolism of CP-122,721 ((2S,3S)-2-phenyl-3-[(5-trifluoromethoxy-2-methoxy)benzylamino]piperidine), a non-peptide antagonist of the substance P receptor. Drug Metab Pharmacokinet. 2007 Oct;22(5):336-49.
3 Metabolism, pharmacokinetics, and excretion of the substance P receptor antagonist CP-122,721 in humans: structural characterization of the novel major circulating metabolite 5-trifluoromethoxy salicylic acid by high-performance liquid chromatography-tandem mass spectrometry and NMR spectroscopy
4 Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics
5 Cytochrome P450 isozymes involved in the metabolism of phenol, a benzene metabolite. Toxicol Lett. 2001 Dec 15;125(1-3):117-23.

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