General Information of This Metabolic Reaction (MR) (ID: MR006427)
Formula Reactant RO-111163 Product Moclobemide M1
Reactant Info Product Info
Metabolic Enzyme Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - C-oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006435 RO-111163 Moclobemide M3 Oxidation - Aromatic hydroxylation RO-111163 [1]
MR006433 RO-111163 Moclobemide M5 Oxidation - N-oxidation RO-111163 [1]
MR006436 RO-111163 Moclobemide M9 Oxidation - Oxidationn deamination RO-111163 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006428 Moclobemide M1 Moclobemide M16 Oxidation - Oxidationn RO-111163 [1]
MR006431 Moclobemide M1 Moclobemide M2 Multi-steps Reaction - Oxidationn; reduction RO-111163 [1]
MR006432 Moclobemide M1 Moclobemide M7 Multi-steps Reaction - Oxidationn; reduction RO-111163 [1]
References
1 Biotransformation of moclobemide in humans

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