| General Information of This Metabolic Reaction (MR) (ID:
MR006438) |
| Formula |
Reactant |
RSD-1235 |
Product |
RSD-1385 |
|
Reactant Info
|
Product Info
|
|
Metabolic Enzyme
|
Cytochrome P450 2D6 (CYP2D6)
|
DME Info
|
|
Metabolic Type
|
Oxidation
-
4-O-demethylation
|
|
|
|
|
|
|
|
| Other MR(s) Related to The Reactant of This MR |
|
Other MR(s) That Metabolize The Reactant of This MR
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| References |
| 1 |
Pharmacokinetics of novel atrial-selective antiarrhythmic agent vernakalant hydrochloride injection (RSD1235): influence of CYP2D6 expression and other factors. J Clin Pharmacol. 2009 Jan;49(1):17-29.
|
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