Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006465)
Formula Reactant SR-4233 Product Tirapazamine radical
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2E1 (CYP2E1) DME Info
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006466 Tirapazamine radical SR-4317 Unclear SR-4233 [1]
References
1 Molecular mechanisms of tirapazamine (SR 4233, Win 59075)-induced hepatocyte toxicity under low oxygen concentrations. Br J Cancer. 1995 Apr;71(4):780-5.

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