Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006508)
Formula
SVG example
Reactant ANW-43703 Product Salicyuric acid
Reactant Info Product Info
Metabolic Enzyme N-acetyltransferase 2 (NAT2) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006504 ANW-43703 Gentistic acid Oxidation - Aromatic hydroxylation ANW-43703 [1]
MR006506 ANW-43703 Salicylacyl glucuronide Conjugation - Conjugation ANW-43703 [1], [2]
MR006507 ANW-43703 Salicylphenol glucuronide Conjugation - Conjugation ANW-43703 [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006505 Gentistic acid Gentisuric acid Unclear ANW-43703 [1], [2]
References
1 Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450. Eur J Pharm Sci. 2015 Jun 20;73:49-56.
2 Polymorphisms of Aspirin-Metabolizing Enzymes CYP2C9, NAT2 and UGT1A6 in Aspirin-Intolerant Urticaria. Allergy Asthma Immunol Res. 2011 Oct;3(4):273-6.

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