Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006535)
Formula
SVG example
N-demethylation
Reactant 4-Chloro-(a-methyl-a-phenyl) benzenemethanol Product 1-Chloro-4-(1-phenylethenyl)-benzene
Reactant Info Product Info
Metabolic Type Oxidation - N-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013157 Clemastine Clemastine Metabolite M3 Unclear - Unclear Clemastine [1]
MR006532 Clemastine fumarate 4-Chloro-(a-methyl-a-phenyl) benzenemethanol Unclear Clemastine fumarate [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006533 4-Chloro-(a-methyl-a-phenyl) benzenemethanol 1-(4-Chlorophenyl)-1-phenyl-1,2-ethandiol Oxidation - N-oxidation Clemastine fumarate [1]
MR006537 4-Chloro-(a-methyl-a-phenyl) benzenemethanol 4-Chlorophenyl-phenyl methanone Oxidation - N-demethylation Clemastine fumarate [1]
MR013162 Clemastine Metabolite M3 Clemastine Metabolite M2 Unclear - Unclear Clemastine [1]
MR013158 Clemastine Metabolite M3 Clemastine Metabolite M6 Unclear - Unclear Clemastine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006536 1-Chloro-4-(1-phenylethenyl)-benzene -[1-(4-Chlorophenyl)ethenyl]-phenol Oxidation - Hydrolyzationn Clemastine fumarate [1]
MR013161 Clemastine Metabolite M1 Clemastine Metabolite M4,M5 Unclear - Unclear Clemastine [1]
References
1 Identification of urinary metabolites of clemastine after oral administration to man

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