Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006537)
Formula
SVG example
N-demethylation
Reactant 4-Chloro-(a-methyl-a-phenyl) benzenemethanol Product 4-Chlorophenyl-phenyl methanone
Reactant Info Product Info
Metabolic Type Oxidation - N-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013157 Clemastine Clemastine Metabolite M3 Unclear - Unclear Clemastine [1]
MR006532 Clemastine fumarate 4-Chloro-(a-methyl-a-phenyl) benzenemethanol Unclear Clemastine fumarate [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006533 4-Chloro-(a-methyl-a-phenyl) benzenemethanol 1-(4-Chlorophenyl)-1-phenyl-1,2-ethandiol Oxidation - N-oxidation Clemastine fumarate [1]
MR006535 4-Chloro-(a-methyl-a-phenyl) benzenemethanol 1-Chloro-4-(1-phenylethenyl)-benzene Oxidation - N-demethylation Clemastine fumarate [1]
MR013160 Clemastine Metabolite M3 Clemastine Metabolite M1 Unclear - Unclear Clemastine [1]
MR013158 Clemastine Metabolite M3 Clemastine Metabolite M6 Unclear - Unclear Clemastine [1]
References
1 Identification of urinary metabolites of clemastine after oral administration to man

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